Neuraptive Therapeutics
Rapid repair & recovery of acutely injured peripheral nerves

Neuraptive is bringing the world’s first truly therapeutic solution for the repair of cut and crushed peripheral nerves. Based on extensive preclinical and early clinical testing, this technology (AxoFuse) has the potential to advance the recovery cycle and improve the final outcome dramatically.

What Is AxoFuse?

AxoFuse consists of three (3) sterile solutions and a device for focal, topical application (directly to the affected nerve) that, when applied sequentially according to the instructions for use, comprise a therapeutic addition to standard surgical repair (microsuturing) for patients with acute peripheral nerve injuries. The process is referred to as PEG-fusion. The delivery device component of the AxoFuse kit serves to concentrate drug exposure at the injury site and protect the surrounding tissues from exposure.

Extensive testing in animals with peripheral nerve injuries has demonstrated that PEG-fusion results in dramatically faster and more improved outcomes compared with animals treated with the contemporary standard of care in clinical practice. Use of the AxoFuse delivery device with PEG-fusion has demonstrated similarly rapid and improved injury recovery as PEG-fusion alone with the added benefit of tissue protection.

AxoFuse is being developed for use within 2-3 days of traumatic injuries resulting in peripheral nerve damage. The product is not currently available for sale or for use in clinical practice.

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